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International Journal of STD & AIDS

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First published on 2 November 2009, doi:10.1258/ijsa.2009.009167
International Journal of STD & AIDS 2010;21:138.
A more recent version of this article appeared on February 1, 2010
© 2009 Royal Society of Medicine Press

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AUDIT REPORT

Oropharyngeal gonorrhoea: rate of co-infection with sexually transmitted infection, antibiotic susceptibility and treatment outcome

K Manavi MD FRCP , F Zafar MBChB and H Shahid MBChB

Department of Genitourinary Medicine, Whittall Street Clinic, Whittall Street, Birmingham B4 6DH, UK

Correspondence to: K Manavi Email: tirbad{at}yahoo.com

The aim of the present study was to investigate the rate of co-infections with other sexually transmitted infections (STIs), antibiotic susceptibility and management of oropharyngeal gonorrhoea diagnosed in a busy genitourinary medicine clinic. The method involved a retrospective study on consecutive patients diagnosed with oropharyngeal gonorrhoea. A total of 131 patients were diagnosed with oropharyngeal gonorrhoea over the study period. The median age of the infected patients was 28 (interquartile range: 22, 35) years. Ninety (69%) of patients were younger than 24 years. Thirty patients (23%) had only oropharyngeal infection. Twenty-two (17%) patients had resistance to at least one antibiotic. Antibiotic resistance among oropharyngeal gonococci isolates was above 5% between 2000 and 2009. Test-of-cure (TOC) was carried out for only 63 (48%) of patients; none had positive culture. Among 46 isolates treated with cefixime 400 mg/stat, 27 (59%) had TOC; all were negative. Repeat TOC was not carried out for any of the patients. In conclusion, successful management of oropharyngeal gonorrhoea consists of counselling, partner notification and TOC after treatment with appropriate antibiotic.

Key Words: oropharyngeal gonorrhoea • antibiotic susceptibility • co-infection • cefixime


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