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International Journal of STD & AIDS

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Int J STD AIDS 2009;20:410-413
doi:10.1258/ijsa.2008.008353
© 2009 Royal Society of Medicine Press

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Original research articles

Presentation and survival of patients with AIDS-related Kaposi's sarcoma in Jos, Nigeria

P A Agaba FWACP * , H M Sule FMCGP *, R O Ojoh FWACP *, Z Hassan BmBcH *, L Apena HND *, M A Mu'azu MSc *, B Badung MSc *, O O Agbaji FMCP *, J A Idoko FMCP * and P Kanki DSc {dagger}

* AIDS Prevention Initiative Nigeria (APIN) Centre, Jos University Teaching Hospital, Jos, Nigeria; {dagger} Harvard School of Public Health, Boston, MA, USA

Correspondence to: Patricia A Agaba, AIDS Prevention Initiative Nigeria Plus (APIN Plus), Jos University Teaching Hospital, P.M.B. 2076, Jos, Plateau State, Nigeria Email: ellagaba{at}yahoo.com

AIDS-related Kaposi's sarcoma (AIDS-KS) remains a significant cause of morbidity and mortality. We describe the pattern of presentation and survival in Jos, Nigeria. We identified 48 HIV-positive patients with AIDS-KS and matched them for age and sex with an equal number of HIV-positive patients without AIDS-KS. We compared their clinical, immunological, virological characteristics and survival. They were similar in age and body mass index profile but patients with AIDS-KS had more tuberculosis co-infection (P, 0.02), lower median CD4 count (P, 0.003) and higher mortality (P, 0.002). Surprisingly, patients with AIDS-KS had lower levels of median viral load (29,347 copies/mL) compared with controls (80,533 copies/mL). We recommend specific AIDS-KS therapy in addition to highly active antiretroviral therapy in order to improve survival.

Key Words: AIDS-related Kaposi's sarcoma • survival • Nigeria


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