International Journal of STD & AIDS > Volume 20, Number 4 > Pp. 274-275

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Seddon, J Articles by Ferrand, R A Search for Related Content PubMed PubMed Citation Social Bookmarking                      What's this?

Case reports

Recurrence of cryptococcal meningitis in HIV-infected patients following immune reconstitution

J Seddon MBBS MRCP ^* , N Mangeya MBChB ^* , R F Miller FRCP   , E L Corbett PhD MRCP ^*  and R A Ferrand MSc MRCP ^*  

^* Biomedical Research and Training Institute; Department of Medicine, University of Zimbabwe, Harare, Zimbabwe; Research Department of Infection and Population Health, Centre for Sexual Health and HIV Research, University College London, London WC1E 6JB; Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK

Correspondence to: Professor Robert F Miller Email: rmiller{at}gum.ucl.ac.uk

Two HIV-infected patients had recurrent cryptococcal meningitis (CM) despite treatment with fluconazole and immune reconstitution with combination antiretroviral therapy (CART). Following treatment of CM with fluconazole, lumbar puncture should be performed either after completion of induction treatment for CM or before starting CART, in order to confirm cerebrospinal fluid sterility.

Key Words: HIV infection • cryptococcal meningitis • fluconazole • IRIS

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?