International Journal of STD & AIDS > Volume 20, Number 3 > Pp. 205-206

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Skidmore, S Articles by Smit, E Search for Related Content PubMed PubMed Citation Social Bookmarking                      What's this?

Case reports

A case study of delayed HIV-1 seroconversion highlights the need for Combo assays

S Skidmore PhD FRCPath  ^*, S Devendra FRCPI , J Weaver RMN RGN , J Short MRCP MRCPath , H Osman MBBCh FRCPath  and E Smit MMed FRCPath(SA) 

^* Department of Microbiology, Shrewsbury and Telford Hospital NHS Trust, Telford TF1 6TF; Department of Genito-urinary Medicine, Telford and Wrekin NHS PCT, Telford TF1 6TF; Department of Sexual Health, Heartlands Hospital, Birmingham B9 5SS; Health Protection Agency Public Health Laboratory, Heartlands Hospital, Birmingham B9 5SS, UK

Correspondence to: Dr S Skidmore Email: sue.skidmore{at}sath.nhs.uk

This report describes a case in which a patient took at least four months to seroconvert to anti-HIV positivity. A concomitant CMV infection probably contributed to the profound immune suppression observed. It is essential that fourth generation HIV antigen/antibody combo assays be used to ensure that such cases are not missed.

Key Words: HIV-seroconversion • HIV fourth generation assays • concomitant infections

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?