International Journal of STD & AIDS > Volume 20, Number 11 > Pp. 771-774

This Article Full Text Full Text (PDF) All Versions of this Article: ijsa.2009.009092v1 ijsa.2009.009092v2 20/11/771    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Sud, N Articles by Gupta, M PubMed PubMed Citation Social Bookmarking                      What's this?

Original research articles

Mucocutaneous manifestations in 150 HIV-infected Indian patients and their relationship with CD4 lymphocyte counts

N Sud MBBS ^*, V Shanker MBBS MD ^* , A Sharma MBBS MD , N L Sharma MBBS MD ^* and M Gupta MBBS MD ^*

^* Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College, Shimla, India; Department of Medicine, Indira Gandhi Medical College, Shimla, India

Correspondence to: Dr V Shanker, Department of Dermatology and Venereology, Indira Gandhi Medical College, Shimla 171001, Himachal Pradesh, India Emails: nehasud{at}gmail.com; shankervinay{at}hotmail.com

Mucocutaneous findings in 150 HIV+ve cases (F, 79; M, 71) were evaluated over a one-year period. Mucocutaneous manifestations were seen in 96% with 2.9 mean number of dermatoses and mean cluster of differentiation (CD4) count of 196.33 cells/mm³. The highest number of mean dermatoses, 3.29, was seen in individuals with severe immunosuppression. The most common mucocutaneous manifestation seen was candidiasis (35.33%), followed by seborrhoeic dermatitis (31.33%), oral pigmentation (29.33%), xerosis/ichthyosis (22.67%), pyodermas (22%), periodontitis (17.33%) and nail pigmentation (16.67%). Patient stratification according to the WHO immunological staging, according to CD4 counts, showed a statistically significant association (P < 0.05) for candidiasis, scabies, paronychia, oral pigmentation and diffuse hair loss. Nail and oral pigmentary changes, trichomegaly and subcutaneous fungal infections caused by dermatophytes were highlights of the study. Incidences of xerosis/ichthyosis, pyodermas, scabies and molluscum contagiosum reported in our study were higher and pruritic popular eruptions was lower than those in previous Indian studies. Cutaneous neoplasms were not seen in the present study.

Key Words: HIV • CD4 counts • mucocutaneous manifestations

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?