International Journal of STD & AIDS > Volume 19, Number 9 > Pp. 644-645

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Case reports

Successful prevention of multidrug resistant HIV mother-to-child transmission with enfuvirtide use in late pregnancy

Giordano Madeddu MD ^* , Giovanna Maria Calia MD ^*, Maria Licinia Campus MD ^*, Carla Lovigu MD ^*, Marco Mannazzu MD ^*, Paolina Olmeo MD , Maria Graziella Mela MD  and Maria Stella Mura MD ^*

^* Department of Infectious Diseases; Department of Pediatric Infectious Diseases, University of Sassari, Sassari, Italy

Correspondence to: Dr Giordano Madeddu, Istituto di Malattie Infettive, Università degli Studi di Sassari, Via De Nicola 1, 07100 Sassari, Italy Email: giordano.madeddu{at}uniss.it

The availability of antiretroviral therapy has dramatically reduced the risk of HIV mother-to-child transmission (MTCT). However, mothers infected with multidrug resistant HIV (MDR-HIV) are at increased risk of MTCT. We report the case of a pregnant patient infected with MDR-HIV in whom MTCT was avoided with enfuvirtide use in late pregnancy and elective caesarean section.

Key Words: HIV • mother-to-child transmission • enfuvirtide

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