International Journal of STD & AIDS > Volume 19, Number 6 > Pp. 414-415

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Audit reports

Audit of the management of antiretroviral treatment-naïve HIV patients in Greater Manchester, UK

Libue Ratcliffe MRCP DTM&H ^*, Orla McQuillan MRCP , Stephen P Higgins FRCP , Edmund G L Wilkins FRCP FRCPath ^* and F J Vilar FRCP MD ^* 

^* Monsall Unit, Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, The Pennine Acute Hospitals NHS Trust; Department of Genitourinary Medicine, Manchester Royal Infirmary, Central Manchester and Manchester Children's University Hospitals NHS Trust; Department of Genitourinary Medicine, North Manchester General Hospital, The Pennine Acute Hospitals NHS Trust, Manchester, UK

Correspondence to: Dr F J Vilar, Monsall Unit, Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Delaunays Road, Manchester M8 5RB, UK Email: Javier.Vilar{at}pat.nhs.uk

We evaluated the management of antiretroviral treatment (ART)-naïve HIV-positive patients in Greater Manchester against the 2005 British HIV association (BHIVA) guidelines. Fifty-seven HIV patients (median age 36 years, 61% males, 53% black Africans) commenced their first ART regimen between 1 October and 31 December 2005. Most of them presented with advanced HIV disease (74% had CD4 lymphocytes <200 and 33% were Centers for Disease Control and Prevention stage C) and 51% commenced ART within three months of their HIV diagnosis. Ninety-six percent had baseline laboratory investigations performed but only 53% had baseline blood pressure estimation. Only 25% had urinalysis performed. A combination of two nucleoside reverse transcriptase inhibitors (NRTI) and one non-NRTI was chosen in 76% of patients. Eighty-two percent of patients had a clinical review and blood tests within five weeks of starting treatment.

Key Words: treatment naïve • human immunodeficiency virus • audit

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