International Journal of STD & AIDS > Volume 19, Number 4 > Pp. 241-242

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Original research articles

Changes in the provision of post-exposure prophylaxis for HIV after sexual exposure following introduction of guidelines and publicity campaigns

S Roedling MRCP ^* , I Reeves MRCP , A J Copas MSc PhD , A Beattie MRCGP ^*, S G Edwards FRCP ^*, M Fisher FRCP  and P Benn MRCP ^*

^* Department of Genitourinary Medicine, Mortimer Market Centre, Camden PCT, London WC1E 6JB; Department of Genitourinary Medicine/HIV, Brighton and Sussex University Hospitals NHS Trust, Brighton BN1 5BE; Centre for HIV and Sexual Health Research, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, University College London, London WC1E 6JB, UK

Correspondence to: Dr S A Roedling, Department of Genitourinary Medicine, Camden PCT, Mortimer Market Centre, off Capper Street, London WC1E 6JB, UK Email: sherie.roedling{at}camdenpct.nhs.uk

In July 2004, British Association of Sexual Health and HIV (BASHH) published guidelines for post-exposure prophylaxis following sexual exposure (PEPSE) and the Terence Higgins Trust (THT) launched a campaign promoting PEPSE among men who have sex with men (MSM). We evaluated subsequent changes in PEPSE attendances. Individuals requesting PEPSE in 2004 were identified from clinic databases. Comparisons of clinical data, exposure characteristics and follow-up were made pre and post campaign. Data were available for 197/216 (91%) PEP attendances. The proportion requesting PEP following sexual exposure increased significantly following the campaign. The majority commencing PEPSE were MSM, with the proportion of MSM increasing significantly from 36/46 (78%) pre to 76/80 (95%) following the campaign. Most prescriptions were in high-risk groups and within guidelines. Times to initiation and completion rates were unchanged. Access to PEPSE following the THT campaign and introduction of BASHH guidelines increased. Promotion of earlier initiation of PEPSE and improvement of completion and follow-up is required.

Key Words: post-exposure prophylaxis • HIV infection • antiretroviral drugs • PEPSE

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