International Journal of STD & AIDS > Volume 19, Number 12 > Pp. 805-809

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Tinmouth, J Articles by Wood, H Search for Related Content PubMed PubMed Citation Social Bookmarking                      What's this?

Original research articles

Is there a reservoir of sub-clinical lymphogranuloma venereum and non-LGV Chlamydia trachomatis infection in men who have sex with men?

J Tinmouth MD FRCPC ^* , M W Gilmour PhD , C Kovacs MD FRCP , R Kropp BSc MPH , L Mitterni BSW ^**, A Rachlis MD FRCPC , S Richards BSc ND , I Salit MD , R Sikri MD ^**, G R Valencia MD CRC ^***, T Wesson MD DH&TM , T Wong MD FRCPC  and H Wood PhD 

^* Division of Gastroenterology, Department of Medicine Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room HG40, Toronto, Ontario M4 N 3M5; Molecular Diagnostics for Special Bacteriology, National Microbiology Laboratory, Winnipeg, Manitoba; Maple Leaf Medical, Toronto, Ontario; Community Acquired Infections Division, Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Ontario; ^** Hassle Free Clinic, Toronto, Ontario; Division of Infectious Diseases Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario; Research Assistant, Sunnybrook Health Sciences Centre, Toronto, Ontario; Division of Infectious Diseases Department of Medicine, University Health Network, Eaton 13-215, Toronto, Ontario; ^*** Clinical Research Associate, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; London School of Hygiene and Tropical Medicine, London, UK; Public Health Agency of Canada and, University of Ottawa, Ottawa, Ontario; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

Correspondence to: Dr Jill Tinmouth Email: jill.tinmouth{at}sunnybrook.ca

The aim of this study was to determine if a reservoir of sub-clinical LGV infection exists in men who have sex with men (MSM), as this finding might account for the recent rise in lymphogranuloma venereum (LGV) Chlamydia trachomatis infections among MSM in Canada. MSM without proctitis were enrolled between January and August 2006 in a cross-sectional study. Rectal, urine, serology and pharyngeal specimens were tested for specific C. trachomatis serovars. The median age of the 253 participants was 43 years; 53% were HIV+. We found no active cases of LGV infection; but 20 (8%) participants had positive serology. Thirteen participants (5%) had non-LGV C. trachomatis infections. Unprotected anopenetrative intercourse, rectal enema and drug use were associated with non-LGV C. trachomatis infection. Sub-clinical rectal non-LGV C. trachomatis infection was relatively common but LGV was not identified in our sample. Further studies of screening for non-LGV chlamydia infection in MSM are needed.

Key Words: lymphogranuloma venerum • Chlamydia trachomatis • proctitis • prevalence • men who have sex with men

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				A. A. Abdul-Sater, E. Koo, G. Hacker, and D. M. Ojcius Inflammasome-dependent Caspase-1 Activation in Cervical Epithelial Cells Stimulates Growth of the Intracellular Pathogen Chlamydia trachomatis J. Biol. Chem., September 25, 2009; 284(39): 26789 - 26796. [Abstract] [Full Text] [PDF]