International Journal of STD & AIDS > Volume 19, Number 11 > Pp. 784-785

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Case reports

A very particular case of long-term non-progressor: nineteen consecutive years of follow-up in the absence of any detectable HIV-1 viraemia

R Manfredi MD , S Sabbatani MD, C Fulgaro MD and G Fasulo MD

Division of Infectious Diseases, Department of Clinical and Experimental Medicine, University of Bologna ‘Alma Mater Studiorum’, S. Orsola-Malpighi Hospital, Bologna, Italy

Correspondence to: Roberto Manfredi, Associate Professor, Division of Infectious Diseases, University of Bologna, c/o Infectious Diseases, S. Orsola Hospital, Via Massarenti 11, I-40138 Bologna, Italy Email: Roberto.manfredi{at}unibo.it

A case of extremely prolonged non-progression of HIV-1 infection, characterized by 19 consecutive years of persistently undetectable viraemia (or no laboratory markers of HIV replication) is presented and discussed based on recent literature issues regarding virological and immunological outcome of the natural history of HIV-1 infection.

Key Words: long-term non-progressor • HIV-1 viraemia • undetectable viral load • case report • 19-year follow-up

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