International Journal of STD & AIDS > Volume 19, Number 10 > Pp. 715-716

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Case reports

Topical cidofovir for severe warts in a patient affected by AIDS and Hodgkin's lymphoma

G V L De Socio MD ^* , S Simonetti MD , D Rosignoli MD ^*, P Minga MD , G M Tomassini MD  and F Baldelli MD ^*

^* Department of Infectious Diseases; Department of Dermatology; Department of Hematology and Clinical Immunology, ‘Santa Maria della Misericordia’ Hospital, University of Perugia, Piazzale Menghini, 1 – 06129 Perugia, Italy

Correspondence to: Dr Giuseppe Vittorio Luigi De Socio Email: giuseppedesocio{at}yahoo.it

We describe a 42-year-old man with AIDS and Hodgkin's lymphoma whose severe and recalcitrant cutaneous warts resolved following treatment with local 1% cidofovir. Clinically significant improvements were observed in a two-week period of therapy. In advanced HIV disease complicated by additional haematological malignancy, cutaneous warts may be difficult to treat and present a challenge for the attending physicians. In similar clinical condition topical anti-human papillomavirus therapy may prove to be safe and curative.

Key Words: verruca vulgaris • HIV • lymphoma • cidofovir • human papillomavirus

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