International Journal of STD & AIDS > Volume 19, Number 1 > Pp. 62-64

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CASE REPORT

Cerebral syphilitic gumma in HIV-infected patients: case report and review

Letícia S Weinert MD, Rafael S Scheffel MD, Gabriela Zoratto MD, Vinícius Samios MD, Marcelo W Jeffmann MD, José Miguel Dora MD and Luciano Z Goldani MD 

Infectious Diseases Unit, Department of Internal Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

Correspondence to: Luciano Z Goldani, Serviço de Medicina Interna, Hospital de Clínicas de Porto alegre, Ramiro Barcelos 2350, 90035-002 Porto Alegre, RS, Brazil Email: lgoldani{at}ufrgs.br

Neurosyphilis presenting as a cerebral gumma is an uncommon event. To date there are seven cases of cerebral gumma reported in human immunodeficiency virus (HIV)-infected patients. We describe a HIV-infected patient with neurosyphilis presenting as an expanding central nervous system lesion and unremarkable cerebrospinal fluid analysis. This case report illustrates the clinical and therapeutic aspects of syphilitic gumma in HIV-infected patients.

Key Words: HIV • AIDS • neurosyphilis • syphilis • gumma • central nervous system

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