International Journal of STD & AIDS > Volume 18, Number 11 > Pp. 727-731

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Review

The incidence of pelvic inflammatory disease in untreated women infected with Chlamydia trachomatis: a structured review

W L Risser and J M H Risser

Department of Pediatrics, University of Texas - Houston Medical School, Houston, TX, USA; Division of Epidemiology, University of Texas School of Public Health, Houston, TX, USA

Because of the long-term consequences of pelvic inflammatory disease (PID), the cost-effectiveness of Chlamydia trachomatis screening depends in part on the incidence of PID in untreated, chlamydia-infected women. The aim of this study was to evaluate the original research assessing the incidence of PID following C. trachomatis infection. We conducted a thorough search of the literature and selected all available prospective cohort studies. Six studies had original data: the incidence of PID varied from 0% (97.5% confidence interval [CI] 0–12%) during one year of follow-up of 30 women to 30% (95% CI 12–54%) during 50 days of follow-up of 20 women. Studies that included asymptomatic women in other settings reported a lower incidence than those that evaluated women in sexually transmitted disease clinics. In conclusion, no study was of a size or quality to answer our research question definitively. Investigators and clinicians planning chlamydia-screening programmes need to be cognizant of the inconclusive incidence data.

Key Words: CHLAMYDIA TRACHOMATIS • PELVIC INFLAMMATORY DISEASE • EPIDEMIOLOGY

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This article has been cited by other articles:

				A. Aghaizu, H. Atherton, H. Mallinson, I. Simms, S. Kerry, P. Oakeshott, and P. E Hay Incidence of pelvic inflammatory disease in untreated women infected with Chlamydia trachomatis Int J STD AIDS, April 1, 2008; 19(4): 283 - 283. [Full Text] [PDF]

				I Simms and P Horner Has the incidence of pelvic inflammatory disease following chlamydial infection been overestimated? Int J STD AIDS, April 1, 2008; 19(4): 285 - 286. [Full Text] [PDF]