International Journal of STD & AIDS > Volume 18, Number 1 > Pp. 11-16

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Review - continuing education (CPD)

Lymphogranuloma venereum: an emerging cause of proctitis in men who have sex with men

Daniel Richardson and David Goldmeier

Department of HIV and Genitourinary Medicine, Royal Sussex County Hospital, Brighton BN2 5BE, UK; Jefferiss Wing, St Mary's Hospital, London W2 1NY, UK

Before 2003, lymphogranuloma venereum (LGV) was rare in developed nations. Several large clusters of LGV in men who have sex with men have been reported across Europe and in the United States of America (USA) since 2003. LGV is caused by L1, L2 and L3 serovars of Chlamydia trachomatis and is a sexually transmitted infection. LGV causes genital ulcers, infected inguinal lymph nodes (buboes) and proctitis/proctocolitis. Treatment with a three-week course of doxycycline prevents rectal strictures, bowel obstruction, bowel perforation and possibly death. Clinicians seeing men who have sex with men with inguinal lymphadenopathy and bowel symptoms should be aware of this current epidemic.

Key Words: LYMPHOGRANULOMA VENEREUM • LGV • CHLAMYDIA TRACHOMATIS • PROCTITIS • PROCTOCOLITIS • MEN WHO HAVE SEX WITH MEN

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				S. Alexander, I. M. C. Martin, and C. Ison A comparison of two methods for the diagnosis of lymphogranuloma venereum J. Med. Microbiol., August 1, 2008; 57(8): 962 - 965. [Abstract] [Full Text] [PDF]