International Journal of STD & AIDS > Volume 17, Number 5 > Pp. 285-288

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Original research articles

Mycoplasma genitalium is associated with symptomatic urethritis

A Leung, K Eastick, L E Haddon, C K Horn, D Ahuja and P J Horner

Department of Genitourinary Medicine, Bristol Royal Infirmary, Bristol BS2 8AS, UK; Genitourinary Infections Reference Laboratory, Bristol, UK; Department of Genitourinary Medicine, Royal Cornwall Hospital, Truro, UK; Department of Genitourinary Medicine, Royal United Hospital, Bath, UK; Department of Genitourinary Medicine, Bristol Royal Infirmary, Bristol BS2 8AS, UK; Department of Genitourinary Medicine, Bristol Royal Infirmary, Bristol BS2 8AS, UK; Clinical Sciences South Bristol, University of Bristol, Bristol BS2 8AS, UK

In order to further investigate the epidemiology of Mycoplasma genitalium, 680 men attending departments of genitourinary medicine in Bristol, Bath and Truro were studied. M. genitalium was detected in 36 men (5.3%) and was present at all three clinics. Clinically, both urethritis and the presence of a urethral discharge and/or dysuria, but not penile irritation were independently associated with the detection of M. genitalium, the former being with the strongest association (odds ratio [OR] 10.76, 95% confidence interval [CI] [3.10–37.29], P < 0.0001; OR 3.01, 95% CI [1.28–7.05], P = 0.011 and OR 1.28, 95% CI [0.61–2.69], P = 0.51, respectively). In men with urethritis, those with a discharge and/or dysuria were more likely to have M. genitalium detected (OR 2.61, 95% CI [1.09–6.25], P = 0.032). We found no association with younger age or a recent change of sexual partner. In conclusion, M. genitalium is associated with symptomatic urethritis.

Key Words: MYCOPLASMA GENITALIUM • URETHRITIS

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