International Journal of STD & AIDS > Volume 17, Number 3 > Pp. 180-184

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Original research articles

Will sexual risk behaviour increase after being vaccinated for AIDS?

Richard A Crosby and David R Holtgrave

College of Public Health, University of Kentucky, Lexington, KY, USA; Rollins School of Public Health, Department of Behavioral Sciences & Health Education, Lexington, KY, USA; Emory Center for AIDS Research, Lexington, KY, USA

The question of whether people will engage in greater levels of HIV-associated risk behaviour after receiving an AIDS vaccine has not been sufficiently investigated. Three objectives were: (1) assess the likelihood that people will engage in greater levels of HIV-risk behaviour after receiving an AIDS vaccine; (2) determine the association of increases with vaccination intent; and (3) identify differences between people who would and would not increase their HIV-risk behaviour after vaccination.

A cross-sectional survey was conducted of 278 adults from three populations: gay men, African-American women, and persons who used illicit drugs.

Nearly one-quarter of the sample indicated a likelihood that their HIV-risk behaviour would increase after vaccination. This increase was positively associated (r = 0.24) with increased intent to be vaccinated. Previous worry about having HIV (adjusted odds ratio [AOR] = 3.4, P = 0.004), being 32 years of age or older (AOR = 2.9, P = 0.0007), and having less than a high school education (AOR = 2.3, P = 0.027) were each associated with a post-vaccination increase in HIV risk.

With the seemingly real potential for increased HIV-risk behaviours after being vaccinated against AIDS, intervention studies are warranted to identify strategies with potential to minimize this phenomenon.

Key Words: AIDS VACCINE • SEXUAL RISK • BEHAVIOUR • HIV

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